Gainesville 5-star Hotels
Compare rates for 5-star hotels in Gainesville, FL from hundreds of popular travel sites on HotelsCombined.
2 guests, 1 room
...and more
Learn why travelers love HotelsCombined
Travel insights for hotels in Gainesville
Use our HotelsCombined data-powered tips to help you find your next hotel in Gainesville.
What is the cheapest month to book a hotel in Gainesville?
The cheapest month to book a hotel in Gainesville is July ($106). Conversely, the most expensive month to stay in Gainesville is November ($385).
What is the cheapest day to stay in a hotel in Gainesville?
The cheapest day to stay in Gainesville is Sunday ($106). On the other hand, travelers can expect to pay the most on Friday, when the average nightly price is $489.
How much is a hotel in Gainesville tonight?
Users have found prices for hotels in Gainesville tonight starting as low as $70, rising to an average cost of $356, based on searches in the last 72 hours. Prices start from $89 for a 4-star hotel in Gainesville for tonight.
How much is a Gainesville hotel room this weekend?
In the past 72 hours, we’ve seen prices for hotels in Gainesville this weekend for as little as $71/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as $114/night. For a 4-star hotel in Gainesville, the cheapest rate recently found was $99/night for this weekend.
How far ahead should you book a hotel in Gainesville?
Save money by booking a hotel at least 7 days before your trip to Gainesville. The lowest price found when booking 7 days ahead was $117 per night.
Other star-rated hotels in Gainesville
Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on October 13, 2026.
Not set on a 5-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Gainesville based on hotel class.
4 stars
3726 Southwest 40th Boulevard, Gainesville, FL, United States
$91
3 stars
4200 Northwest 97th Boulevard, Gainesville, FL, United States
$91
3743 Hull Road, Gainesville, FL, United States
$111
101 Southeast 1st Avenue, Gainesville, FL, United States
$90
4225 Southwest 40th Boulevard, Gainesville, FL, United States
$98
4015 Southwest 43rd Street, Gainesville, FL, United States
$88
2 stars and under
7516 W. Newberry Road, Gainesville, FL, United States
$62
3600 Southwest 42nd Street, Gainesville, FL, United States
$69
6901 Northwest 4th Boulevard, Gainesville, FL, United States
$59
5505 Southwest 41st Boulevard, Gainesville, FL, United States
$64
7413 West Newberry Road, Gainesville, FL, United States
$54
Other accommodations in Gainesville
Find deals on places to stay in Gainesville that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on October 13, 2026.
Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Gainesville.
1250 West University Avenue, Gainesville, FL, United States
0.8 mi from city centre
Free Wi-Fi
Parking
$103
Avg. per night
3743 Hull Road, Gainesville, FL, United States
3.4 mi from city centre
Free Wi-Fi
Parking
$111
Avg. per night
2115 Southwest 13th Street, Gainesville, FL, United States
1.6 mi from city centre
Free Wi-Fi
$119
Avg. per night
Facts about 5-star hotels in Gainesville
Find useful tips and insights about 5-star hotels in Gainesville to help you make the most of your experience. FAQs were last updated on October 13, 2026.
Stay elsewhere in Gainesville
3-Star Hotels
4-Star Hotels
Alternative Stays
Hotels in Florida
Popular Brands
Popular cities