Hotels near Mayo Clinic, Rochester
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Popular hotels near Mayo Clinic
Discover well-known properties in Mayo Clinic that are favored by visitors more than others. There are 155 hotels in Mayo Clinic and price data was last updated on October 6, 2026. The average price for a hotel in Mayo Clinic is .
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All filters20 2nd Avenue Southwest, Rochester, MN, United States
2 restaurants, an indoor pool, and a 24-hour fitness center are available at this smoke-free hotel. WiFi in public areas is free. Additionally, a bar/lounge, a sauna, and a 24-hour business center are onsite.
Pool
Free Wi-Fi
6.9
Good
1854 reviews
Location
0.9 mi from city centre
$137
9 3rd Avenue Northwest, Rochester, MN, United States
This smoke-free hotel features an indoor pool, a fitness center, and a coffee shop/cafe. Free self-serve breakfast and free WiFi in public areas are also provided. Other amenities include self parking, laundry facilities, and a 24-hour front desk.
Pool
Free Wi-Fi
Airport shuttle
7.2
Good
2089 reviews
Location
1.0 mi from city centre
$141
225 South Broadway, Rochester, MN, United States
The Hilton Garden Inn Rochester Downtown is located in the heart of Rochester Minnesota with climate controlled skywalk access to the Mayo Clinic, University of Minnesota Rochester Shops at University Square, Mayo Civic Center, Government Center, numerous restaurants and theaters.
Pool
Free Wi-Fi
8.3
Excellent
446 reviews
Location
0.8 mi from city centre
$136
10 East Center Street, Rochester, MN, United States
The Hilton Rochester Mayo Clinic Area is located in downtown Rochester two blocks from Mayo Clinic and one block from the Mayo Civic Center. Rochester International Airport is 8 miles away with flights to Chicago and Minneapolis. Minneapolis St. Paul International Airport is 80 miles away with frequent shuttle service. Interstate 90 is also 8 miles from downtown providing access from Madison, Chicago, and points east.
Pool
8.6
Excellent
199 reviews
Location
1.0 mi from city centre
$215
161 13th Avenue Southwest, Rochester, MN, United States
Our hotel in Rochester, MN is across the street from Saint Marys hospital with an on-site restaurant and a free shuttle to and from the Mayo Clinic Methodist Campus. Spacious guest rooms are equipped with streaming Netflix, mobile work space, microwave and refrigerator. A NON SMOKING room with a balcony or recliner is available on a request only basis. Visit The Bistro in the morning for a Starbucks beverage or snack on the go. Join us inside or outside at Saints on 2nd Bar and Grill for a variety of delicious choices prepared by our award winning chef. Keep yourself fit while on the road with our well-equipped onsite fitness center and indoor pool and whirlpool. Other useful amenities include a business center with free printing and 24-hour market Productivity and comfort combine in our flexible meeting space with 3 different tech enabled meeting rooms.
Pool
Free Wi-Fi
8.7
Excellent
283 reviews
Location
1.0 mi from city centre
$123
165 13th Avenue Southwest, Rochester, MN, United States
Stay where health and service are just steps away. Located across the street is Saint Marys Hospital and less than a mile away is the Mayo Clinic Methodist campus. Feel at home in our spacious suites, equipped with modern amenities and thoughtful touches, ensuring a relaxing retreat after a day of exploration or medical appointments. Savor a complimentary hot breakfast each morning, unwind at our Wednesday evening social, and stay connected with free WiFi throughout the hotel. Our central location is within walking distance of a variety of restaurants and retailers. We’re just minutes from Downtown Rochester where you will find the Mayo Civic Center and Rochester Art Center. The Rochester International Airport is only a short drive away.
Pool
Free Wi-Fi
9.0
Excellent
152 reviews
Location
1.0 mi from city centre
$127
1211 2nd Street, Rochester, MN, United States
This smoke-free hotel features an indoor pool, a fitness center, and a 24-hour business center. Free full breakfast is provided, as well as free WiFi in public areas, free self parking, and a free area shuttle. Other amenities include a hot tub, coffee/tea in a common area, and a business center.
Pool
Free Wi-Fi
8.1
Excellent
169 reviews
Location
1.0 mi from city centre
$150
101 1st Avenue Southwest, Rochester, MN, United States
Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via underground climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, running and several trails nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at our in new in house restaurant North Stone Kitchen. Business travelers, enjoy spacious guest rooms with work areas and Wi-Fi. All our guest rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury downtown Rochester at Rochester Marriott Mayo Clinic Area.
Pool
Free Wi-Fi
8.4
Excellent
281 reviews
Location
0.9 mi from city centre
$241
441 West Center Street Northwest, Rochester, MN, United States
The Residence Inn Rochester Mayo Clinic Area is conveniently located downtown Rochester, MN within walking distance to the world-famous Mayo Clinic. Enjoy our newly renovated well-appointed 1 or 2 bedroom suite with a sofa bed, kitchen with microwave, full-size fridge, stovetop, dishwasher, and cookware. Complimentary amenities include a hot breakfast each morning, Wi-Fi access, a 24-hour fitness center, and a rooftop patio. Host up to 20 people for a business meeting in the Silver Lake Meeting room. The Residence Inn Rochester Mayo Clinic Area is 9 miles from the Rochester International Airport and provides access to Mayo Clinic via a indoor pedestrian walkway. Our hotel in downtown Rochester, MN is centrally located to St. Mary’s Hospital and Methodist Hospital. Please be aware there is on-going Mayo construction next to us, which may cause noise related concerns during your stay.
Free Wi-Fi
8.1
Excellent
78 reviews
Location
0.9 mi from city centre
$180
Cheapest hotels near Mayo Clinic, Rochester
Discover affordable stays in Mayo Clinic that provide a quality experience without breaking the bank. Hotels in Mayo Clinic can be found for as low as $64 per night. There is currently one property in Mayo Clinic that can be booked for this price. Baymont by Wyndham Rochester Mayo Clinic Area is one of the hotels that can be booked for the lowest price in Mayo Clinic. Price data was last updated on October 6, 2026
At the moment, these hotels offer the lowest nightly rate out of those we've come across close to Mayo Clinic. If you have the flexibility, change the dates selected to compare prices.
1230 South Broadway, Rochester, MN, United States
0.6 mi from city centre
Pool
Free Wi-Fi
Parking
$64
Avg. per night
435 16th Avenue Northwest, Rochester, MN, United States
1.4 mi from city centre
Pool
Free Wi-Fi
Parking
$78
Avg. per night
1215 2nd Street Southwest, Rochester, MN, United States
1.0 mi from city centre
Free Wi-Fi
Parking
$93
Avg. per night
401 6th Street Southwest, Rochester, MN, United States
0.5 mi from city centre
Pool
Free Wi-Fi
Parking
$103
Avg. per night
470 17th Avenue Northwest, Rochester, MN, United States
1.5 mi from city centre
Pool
Free Wi-Fi
Parking
$114
Avg. per night
1125 2nd Street Southwest, Rochester, MN, United States
0.9 mi from city centre
Pool
Free Wi-Fi
Airport shuttle
$119
Avg. per night
155 16th Avenue Southwest, Rochester, MN, United States
1.1 mi from city centre
Pool
Free Wi-Fi
Parking
$120
Avg. per night
123 Fourth Ave. NW, Rochester, MN, United States
1.0 mi from city centre
Free Wi-Fi
Air Conditioning
$122
Avg. per night
Hotel prices near Mayo Clinic
Get a sense of the average price and most popular properties to stay in Mayo Clinic to help you budget for your trip accordingly. Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” badge are the most popular hotels in Mayo Clinic at attractive prices. Price data was last updated on October 6, 2026.
Hotels located in the Mayo Clinic area sorted by price and hotel class. Change the dates at the top of the page to see more options near Mayo Clinic.
4 stars +
10 East Center Street, Rochester, MN, United States
$215
3 stars
9 3rd Avenue Northwest, Rochester, MN, United States
$141
1125 2nd Street Southwest, Rochester, MN, United States
$119
401 6th Street Southwest, Rochester, MN, United States
$103
2 stars and under
435 16th Avenue Northwest, Rochester, MN, United States
$78
1230 South Broadway, Rochester, MN, United States
$64
Other accommodations near Mayo Clinic
Find the perfect hostel, theme hotel, or vacation rental for your stay in Mayo Clinic. There are 155 hotels in Mayo Clinic and price data was last updated on October 6, 2026. The average price for a stay in Mayo Clinic is .
161 13th Avenue Southwest, Rochester, MN, United States
1.0 mi from city centre
Pool
Free Wi-Fi
$123
Avg. per night
123 Fourth Ave. NW, Rochester, MN, United States
1.0 mi from city centre
Free Wi-Fi
Air Conditioning
$122
Avg. per night
441 West Center Street Northwest, Rochester, MN, United States
0.9 mi from city centre
Free Wi-Fi
$180
Avg. per night
Where to stay near Mayo Clinic
Explore different neighborhoods and areas within Mayo Clinic to find the perfect location for your stay. Map data was last updated on October 6, 2026.
Scroll through the map to find hotels close to the Mayo Clinic neighborhood(s) you plan on visiting. More information on a given hotel can be accessed by clicking the hotel's name within the map.
Facts about staying in Mayo Clinic
Find useful tips and insights about staying in Mayo Clinic to help you make the most of your experience. FAQs were last updated on October 6, 2026.
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