The St. Regis Osaka welcomes guests to the heart of beautiful Midosuji, the Champs Elysées of Osaka. Our five-star hotel is located near popular destinations such as Universal Studios Japan, Osaka Aquarium Kaiyukan and the city's premium shopping districts. There is no better address to explore the city center and the neighboring cities of Kyoto and Nara, thanks to our hotel location near the train station. Return for exquisite dining at our on-site restaurants, Rue d'Or, La Veduta, and Teppanyaki WAJO, before discovering the epitome of luxury at the exclusive IRIDIUM featuring SOTHYS Spa. Retreat to our hotel’s iconic 12th-floor terrace with sweeping vistas of the Osaka skyline. Discover unforgettable ambiance and state-of-the-art amenities in five-star hotel accommodations. Our 160 luxury hotel rooms and suites feature spacious layouts and elegantly appointed decor. Every experience our hotel in Osaka, Japan, is enhanced with the St. Regis Butler Service, available any time, day or night.