Hotels in Sikeston, MO

Behind every great day is a great night at the pet-friendly Comfort Inn and Suites Sikeston I-55 hotel in Sikeston, MO. We are conveniently located right near activities and sites like the VF Factory Outlet Mall, Bootheel Golf Club, Sikeston Depot, Veterans Park and Beggs Family Farm. Take advantage of our free hot breakfast, free WiFi, free coffee and guest laundry facilities. Rooms feature flat-screen TVs, hair dryers, coffee makers, irons and ironing boards, microwaves and refrigerators. We also offer membership to the Choice Privileges Program, which gives members the opportunity to earn valuable rewards points toward airline miles, gift cards and free hotel room nights.

Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown and within walking distance to many shops and restaurants. Settle in for a relaxing stay in one of our modern guest rooms. Enjoy the convenience of a mini-refrigerator, microwave, free WiFi, coffeemaker, 42-inch flat-screen TV with premium cable channels and work desk with ergonomic chair. Upgrade to a studio suite for extra space and a separate seating area. Start each day with our free hot breakfast or, if you’re in a hurry, grab one of Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stop by our Treats Shop any time of day or night for a quick snack or beverage. Stay in shape with a workout in our 24-hour fitness center or take a dip in our indoor heated pool. Plan a meeting in our 700 sq. ft. of meeting space fully equipped with A/V equipment.

Country Yard Inn and Suites provides air-conditioned accommodations in Sikeston. This 2-star hotel offers a 24-hour front desk. The hotel also has free WiFi and free private parking. At the hotel, the rooms include a desk, a flat-screen TV, a private bathroom, bed linen and towels. All rooms will provide guests with a microwave. The nearest airport is Cape Girardeau Regional Airport, 27 miles from Country Yard Inn and Suites.

Convenience and service make this Sikeston hotel a popular favorite that's close to Interstates 55 and 57 and Highway 62. Your Best Western Plus Sikeston is pet-friendly, welcoming the entire family whether it’s for a vacation or business trip. Hotels in Sikeston are renowned for hospitality, but the bar is set high at this property. Near the Sikeston Rodeo, there are endless entertainment options that draw travelers from around the country. Business travelers and leisure travelers alike enjoy the homey amenities and great customer service. Looking for the best Sikeston, MO hotels? Our property is affordable and boasts the absolute best service in town. A popular stopping point for travelers, make sure to visit some local favorites like Lambert’s Café, just a few minutes away from this Sikeston hotel. The Azalea Festival is a favorite local event, and there’s always something special happening nearby. Ask a friendly staff member for recommendations or an insider’s tip on must-see destinations. Business travelers with Tyson Foods and Unilever depend on our Sikeston hotel for extended stays. Offering corporate travelers and government employees, such as those with BNSF, the best rates in town guarantees a stress-free trip. Newly renovated and just 20 miles to the Mississippi River, you deserve only the best Sikeston hotel on your next trip. Plus, staying 30 miles to the nearest casino means the best in gaming and entertainment is a short commute away. Reserve your next stay at Best Western Plus Sikeston where the comfort of guests is a top priority! Enjoy your stay.

Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby attractions. Thanks to a convenient location close to I55,I60 and nearby companies, including, Monsanto, Cargill, and Siemens, John Deere, Orgill, Tyson, Unilever and Sikeston Power Plant. In addition, we provide guests with a selection of handy services at our state of the art Business Center. Sikeston is also home to the annual Sikeston Jaycee Bootheel Rodeo, which draws large crowds every August. Our accommodations are close to shops and dining venues. Whether you’re staying in Sikeston, MO for business or pleasure, we have the amenities to satisfy your needs. Connecting to colleagues and family is easy with the free high speed Internet access, and mornings are great with a cup of fresh coffee and gooey cinnamon roll from our complimentary, hot Express Start breakfast bar. Go for a dip in the indoor heated pool or burn calories in our state of the art Fitness Center. If you are looking for lodging in Sikeston, MO, our hotel is the smart choice.