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Hotels in Seneca

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Travel insights for hotels in Seneca

Use our HotelsCombined data-powered tips to help you find your next hotel in Seneca.

What is the cheapest month to book a hotel in Seneca?

The cheapest month to book a hotel in Seneca is January ($97). Conversely, the most expensive month to stay in Seneca is November ($208).

What is the cheapest day to stay in a hotel in Seneca?

The cheapest day to stay in Seneca is Monday ($101). On the other hand, travelers can expect to pay the most on Friday, when the average nightly price is $247.

Find deals

Cheapest hotels in Seneca, South Carolina

Discover affordable stays in Seneca that provide a quality experience without breaking the bank. Hotels in Seneca can be found for as low as $60 per night. There is currently one property in Seneca that can be booked for this price. Days Inn by Wyndham Seneca / Clemson Area is one of the hotels that can be booked for the lowest price in Seneca. Price data was last updated on December 21, 2025
At the moment, these hotels offer the lowest nightly rate out of those we've come across in Seneca. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

11015 North Radio Station Road, Seneca, SC, United States
1.9 mi from city centre
Free Wi-Fi
Air Conditioning
$60
Avg. per night
View Deal
Quality Inn Seneca Us-123
Quality Inn Seneca Us-123

Quality Inn Seneca Us-123

226 Hi-Tech Road, Seneca, SC, United States
2.4 mi from city centre
Free Wi-Fi
Air Conditioning
$66
Avg. per night
View Deal
Best Western Seneca-Clemson
Best Western Seneca-Clemson

Best Western Seneca-Clemson

511 Bypass Highway 123, Seneca, SC, United States
0.8 mi from city centre
Free Wi-Fi
Parking
$79
Avg. per night
View Deal
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

13050 Clemson Boulevard, Seneca, SC, United States
5.1 mi from city centre
Free Wi-Fi
Parking
$105
Avg. per night
View Deal
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

1011 East North 1st Street, Seneca, SC, United States
1.1 mi from city centre
Free Wi-Fi
Parking
$112
Avg. per night
View Deal

Hotel prices in Seneca

Get a sense of the average price and most popular properties to stay in Seneca to help you budget for your trip accordingly. Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” badge are the most popular hotels in Seneca at attractive prices. Price data was last updated on December 21, 2025.
We've come across the following hotels in Seneca with different price and hotel class options. We've also highlighted the most popular hotels and best value within each hotel class.
3 stars
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

1011 East North 1st Street, Seneca, SC, United States
$112
View Deal
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

13050 Clemson Boulevard, Seneca, SC, United States
$105
View Deal
2 stars and under
Quality Inn Seneca Us-123
Quality Inn Seneca Us-123

Quality Inn Seneca Us-123

226 Hi-Tech Road, Seneca, SC, United States
$66
View Deal
Best Western Seneca-Clemson
Best Western Seneca-Clemson

Best Western Seneca-Clemson

511 Bypass Highway 123, Seneca, SC, United States
$79
View Deal
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

11015 North Radio Station Road, Seneca, SC, United States
$60
View Deal

Other accommodations in Seneca

Find the perfect hostel, theme hotel, or vacation rental for your stay in Seneca. There are 226 hotels in Seneca and price data was last updated on December 21, 2025. The average price for a stay in Seneca is $143/night.
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

1011 East North 1st Street, Seneca, SC, United States
1.1 mi from city centre
Free Wi-Fi
Parking
$112
Avg. per night
View Deal
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

13050 Clemson Boulevard, Seneca, SC, United States
5.1 mi from city centre
Free Wi-Fi
Parking
$105
Avg. per night
View Deal
Quality Inn Seneca Us-123
Quality Inn Seneca Us-123

Quality Inn Seneca Us-123

226 Hi-Tech Road, Seneca, SC, United States
2.4 mi from city centre
Free Wi-Fi
Air Conditioning
$66
Avg. per night
View Deal

Where to stay in Seneca

Explore different neighborhoods and areas within Seneca to find the perfect location for your stay. Map data was last updated on December 21, 2025.
Whether you're visiting Seneca for leisure or business, utilize the map to find hotels close to your ideal location. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Seneca

Find useful tips and insights about staying in Seneca to help you make the most of your experience. FAQs were last updated on December 21, 2025.

  • What are the best hotels in Seneca?

    One of the most popular hotels in Seneca is Quality Inn Seneca Us-123, which has been reviewed by 490 users and currently has a rating of 8.0/10. Other top-rated locations include Best Western Seneca-Clemson and Tru by Hilton Seneca Clemson, which have received 7.8/10 and 9.2/10 ratings from our users, respectively.

  • How much is a cheap hotel in Seneca?

    Prices for Seneca hotels have been found for as low as $61/night over the last 3 days. For the coming weekend of Dec 26 to Dec 28, prices for hotels in Seneca start from as low as $87/night.

  • What are some other cities to stay in when visiting South Carolina?

    In addition to Seneca, travelers opt to visit Myrtle Beach when visiting South Carolina. Charleston is also a popular choice to visit.

  • How many hotels are there in Seneca?

    In total, there are 226 hotels to choose from in Seneca, compared to 37,058 properties in South Carolina.

See more FAQs

Find better results for your stay in Seneca

Consider these popular 3-star hotels in Seneca

Stay at one of these Seneca 3-star hotels that users have found on HotelsCombined.
Hampton Inn & Suites Seneca-Clemson Area
Tru by Hilton Seneca Clemson