Vacation rentals in St. Charles

Search and compare St. Charles, MO vacation rentals from hundreds of travel sites on HotelsCombined and save.

...and more

Learn why travelers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customize your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Other accommodations in St. Charles

Find the perfect vacation rental for your stay in St. Charles. There are 113 hotels in St. Charles and price data was last updated on February 9, 2026. The average price for a hotel in St. Charles is .
Ameristar Casino Resort Spa St. Charles
Ameristar Casino Resort Spa St. Charles

Ameristar Casino Resort Spa St. Charles

1 Ameristar Boulevard, St. Charles, MO, United States
1.5 mi from city centre
Free Wi-Fi
Parking
$145
Avg. per night
View Deal
Baymont by Wyndham St. Charles
Baymont by Wyndham St. Charles

Baymont by Wyndham St. Charles

801 Veterans Memorial Parkway, St. Charles, MO, United States
1.3 mi from city centre
$87
Avg. per night
View Deal
Country Inn & Suites by Radisson, St. Charles, MO
Country Inn & Suites by Radisson, St. Charles, MO

Country Inn & Suites by Radisson, St. Charles, MO

1190 South Main Street, St. Charles, MO, United States
1.2 mi from city centre
Pool
Free Wi-Fi
Parking
$83
Avg. per night
View Deal

Where to stay in St. Charles

Explore different neighborhoods and areas within St. Charles to find the perfect location for your stay. Map data was last updated on February 9, 2026.
Use the map to find vacation rentals in St. Charles that are close to the points of interest you'll be frequenting. Clicking a property's name will unlock more information and allow you to book that particular vacation rental.

Facts about staying in St. Charles

Find useful tips and insights about staying in St. Charles to help you make the most of your experience. FAQs were last updated on February 9, 2026.

  • How much does a vacation rental in St. Charles cost?

    $223 per night is how much a vacation rental in St. Charles costs, on average. $52 per night was the cheapest price recently found by our users, though anything for $192 per night or less is a good deal. Keep in mind that St. Charles vacation rental prices fluctuate throughout the year: the most expensive month to book is August, and the cheapest time to book is April.

Find better results for your stay in St. Charles