Vacation rentals in Murphysboro

Search and compare Murphysboro, IL vacation rentals from hundreds of travel sites on HotelsCombined and save.

...and more

Learn why travelers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customize your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Where to stay in Murphysboro

Explore different neighborhoods and areas within Murphysboro to find the perfect location for your stay. Map data was last updated on August 7, 2025.
Scroll to and zoom in on the areas in Murphysboro you plan on visiting to find nearby properties. As an added benefit, users can click a vacation rental they're interesting in to find helpful information and deals for that vacation rental.

Facts about staying in Murphysboro

Find useful tips and insights about staying in Murphysboro to help you make the most of your experience. FAQs were last updated on August 7, 2025.

  • How much does a vacation rental in Murphysboro cost?

    $137 per night is how much a vacation rental in Murphysboro costs, on average. $92 per night was the cheapest price recently found by our users, though anything for $137 per night or less is a good deal. Keep in mind that Murphysboro vacation rental prices fluctuate throughout the year: the most expensive month to book is June, and the cheapest time to book is June.

Find better results for your stay in Murphysboro

Explore these cities in Illinois

Looking to explore Illinois during your trip? These are other popular cities nearby that HotelsCombined users visit
Hotels in Chicago
Hotels in Rosemont
Hotels in Champaign
Hotels in Schaumburg
Hotels in Elgin
Hotels in Galena
Hotels in Gurnee
Hotels in Rantoul
Hotels in Elk Grove Village
Hotels in Rockford
Hotels in Evanston
Hotels in Springfield
Hotels in Lansing
Hotels in Hoffman Estates
Hotels in Ottawa
Hotels in Peoria
Hotels in Marion
Hotels in Tinley Park
Hotels in Bloomington
Hotels in Effingham
Hotels in Downers Grove
Hotels in Naperville
Hotels in Joliet
Hotels in Waukegan
Hotels in Bolingbrook
Hotels in O'Fallon
Hotels in Saint Charles
Hotels in North Chicago
Hotels in Schiller Park
Hotels in Peru
Hotels in Oakbrook Terrace
Hotels in Oak Brook
Hotels in Romeoville
Hotels in Danville
Hotels in Collinsville
Hotels in Normal
Hotels in Elmhurst
Hotels in Carbondale
Hotels in Mattoon
Hotels in Lombard
Hotels in Bridgeview
Hotels in Moline

Search cheap hotels with HotelsCombined. Use the hotel finder to search for the cheapest hotel deal for all major destinations around the world. HotelsCombined searches hundreds of hotel booking sites to help you find hotels and book hotels that suit you best. Since HotelsCombined searches many hotel sites at once, you can find discount hotels quickly, including Hotels Under $50 and Hotels Under $100. Discover hotel discounts now and make your hotel reservation today.