Where to Stay in Rome: Best Neighbourhoods & Hotels for Sightseeing

Rome is a mecca for Italy’s ancient history, blessed with numerous world-famous attractions showcasing the Roman times, such as the Colosseum and Roman Forum. It’s also home to various cultural institutions, high-end fashion strips, charming island communities and excellent dining areas. With so much to see and do, picking the right neighbourhood and hotel in Rome is important.

With more than 400 million annual visitors to HotelsCombined, we’ve found the best hotels and neighbourhoods in Rome for sightseeing. From Borgo and Monti to Trastevere and Esquilino, these popular areas keep you close to Rome’s biggest attractions while also boasting some of the city’s best hotels.

Why You Should Stay in Monti

tourists riding bikes in colle oppio

Photo| Tourists riding bikes in Colle Oppio park in front of colosseum| GETTYIMAGES – TFILM

Rome’s eclectic city-centre neighbourhood, Monti stands out with its bohemian and classic Italian elements, including ancient archaeological sites, family-run eateries, alfresco wine bars and vintage stores. Explore this neighbourhood’s cobbled streets and laneways to discover unique jewellery and funky weekend markets, along with the popular Piazza della Madonna dei Monti.

Must-Do Monti Experiences 

  • Explore the world-famous Colosseum gladiatorial arena.
  • Stroll past shady trees, grassy lawns and ancient remains in the Park of Colle Oppio.
  • Dine on sumptuous Italian cuisine at La Taverna Dei Monti.

Top Hotels in Monti

Roma Luxus Hotel

Roma Luxus Hotel, hotel to stay in rome

Photo| Roma Luxus Hotel| Provided by BOOKING.COM

Housed in an extravagant 18th-century palace, Roma Luxus Hotel combines beautiful Italian design, art and opulence. The comfortable rooms and suites feature hand-crafted furnishings, Italian marble bathrooms and king-size beds. The Classic is ideal for budget-focused travellers, while the Deluxe Suite has a four-person hydromassage bath and furnished terrace with city views.

Indulge in a pampering treatment or massage at the on-site Wellness Spa, which has a Finnish sauna and Turkish Hammam. You can also enjoy Italian and South America fusion cuisine at Madre restaurant or a sumptuous breakfast buffet of fresh fruits and pastries in the Breakfast Room.

Nearby Attractions 

  • Roman Forum (1.1 kilometres)
  • Colosseum (850 metres)
  • Quirinal Palace (400 metres)

Star Rating: 5*
Price: USD 134 – USD 369
Guest Rating: 8.6
Address: Largo Angelicum 4, Monti, Rome, Italy

Palazzo Manfredi

Palazzo Manfredi, hotel to stay in Rome

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Palazzo Manfredi – Relais & Chateaux sits on the site of four barracks and a training school for gladiators fighting in the Colosseum. The 5-star hotel complements its rich history with unparalleled service and on-site luxuries, such as the Michelin-starred AROMA restaurant with its outdoor terrace overlooking the Colosseum. You can also relax with a cocktail or beer at the open-air American Bar.

The rooms at Palazzo Manfredi – Relais & Chateaux include the Prestige, Executive and Master, the latter of which has Colosseum views. You can upgrade to the Grand View Colosseum Suite for two levels of unbridled luxury, including a separate living area and private terrace.

Nearby Attractions

  • Colosseum (350 metres)
  • Park of Colle Oppio (500 metres)
  • Divin Ostilia Italian restaurant (270 metres)

Star Rating: 5*
Price: USD 281 – USD 864
Guest Rating: 8.8
Address: Via Labicana 125, Monti, Rome, Italy

Hotel Location

Why You Should Stay in Borgo

Sant'Angelo Bridge and Castel Sant'Angelo at night

Photo| Sant’Angelo Bridge and Castel Sant’Angelo| GETTYIMAGES – SYLVAIN SONNET

One of Rome’s most recognisable neighbourhoods, Borgo precedes the revered Vatican City and is centred around the prominent Castel Sant’Angelo. This atmospheric neighbourhood showcases rich Italian history and deep religious roots within its museums and institutions. It also features numerous restaurants and shops along Via della Conciliazione.

Must-Do Borgo Experiences

  • Discover the ancient exhibits and sweeping city views at Castel Sant’Angelo.
  • Admire the artwork and inventions of Da Vinci at the Museum Leonardo Da Vinci Experience.
  • Stroll down Via della Conciliazione to the grand Piazza San Pietro in the iconic Vatican City.

Top Hotels in Borgo

Palazzo Cardinal Cesi

Palazzo Cardinal Cesi, hotel to stay in Rome

Photo| Palazzo Cardinal Cesi| Provided by BOOKING.COM

The 4-star Palazzo Cardinal Cesi is housed within a 15th-century palace alongside a small antiques and art museum and library. This intimate hotel has 30 cosy rooms that provide the perfect Roman sanctuary with Italian decor, Cherrywood furnishings, mini bars and complimentary internet. You can also upgrade to the luxe Garden Suite, which has a private entry, inner courtyard and original frescoes.

Begin your day right with a delicious American-style buffet breakfast in The Refectory, which has an outdoor courtyard. You can also request room service or relax in The Library while enjoying alcoholic refreshments from the Cloister bar. Right outside you’ll find the bustling Via della Conciliazione.

Nearby Attractions

  • Vatican City (400 metres)
  • Museum Leonardo Da Vinci Experience (140 metres)
  • Castel Sant’Angelo (600 metres)

Star Rating: 4*
Price: USD 126 – USD 273
Guest Rating: 9
Address: Via Della Conciliazione 51, Borgo, Rome, Italy

Hotel Location

Why You Should Stay in Prati

Palazzo di Giustizia

Photo| Palazzo di Giustizia| GETTYIMAGES – PHILIPP DEMMLER

Despite its close proximity to the city centre, Prati remains one of Rome’s most relaxed neighbourhoods, blessed with wide streets and modern shopping centres within historic buildings. If you’re planning a shopping holiday in Rome, Prati is one of the best neighbourhoods to stay. It also offers exceptional dining and drinking establishments and popular theatres.

Must-Do Prati Experiences

  • Catch an intimate comedic performance at the Teatro Prati.
  • Browse one-of-a-kind boutiques, including luxe female fashion retailers, along Via Cola di Rienzo.
  • Admire the grand architecture and storied history of the prominent Palazzo di Giustizia. 

Top Hotels in Prati

Hotel Vespasiano

Hotel Vespasiano, hotel to stay in Rome

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Hotel Vespasiano expertly blends history with contemporary luxury, providing exceptional services and rooms. The accommodations feature designer Made in Italy furnishings, smart TVs, king-size beds and marble bathrooms with Hi-Fi systems and either a chromotherapy shower or hydromassage bath. Upgrade to the Junior Suite for additional space and the option of a triple room bed configuration.

During your stay, pamper yourself with a rejuvenating treatment at the on-site Exclusive Spa, which also features a sauna, Jacuzzi and Turkish Hammam. You can also dine on a hearty breakfast each morning, book a babysitting service and organise airport transfers at the hotel. 

Nearby Attractions

  • Via Cola di Rienzo’s shops and restaurants (800 metres)
  • Vatican Museums and Sistine Chapel (400 metres)
  • Teatro dell’Angelo (400 metres)

Star Rating: 4*
Price: USD 150 – USD 194
Guest Rating: 9
Address: Via Vespasiano 49, Prati, Rome, Italy

Hotel dei Mellini

Hotel dei Mellini, hotel to stay in Rome

Photo| Hotel dei Mellini| Provided by BOOKING.COM

Nestled on the River Tiber, Hotel dei Mellini is a peaceful holiday haven ideally located for sightseeing, dining and entertainment. The hotel also has an on-site cafeteria-style dining room with Mediterranean-inspired lunch and dinner menus. You can also relax on timber sun loungers on the patio, work out in the gym or grab a cocktail or wine from the bar.

The hotel’s 80 guest rooms are spread across six floors and range from Single and Superior rooms to Suites and seven-person Family Rooms. Each room and suite exudes Italian luxury and flair while also providing complimentary Wi-Fi, mini bars, large desks and heavenly beds. The Suite also has a separate living room and a welcome bottle of Spumante.

Nearby Attractions

  • Mausoleum of Augustus (650 metres)
  • Museo delle Anime del Purgatorio (450 metres)
  • Gelateria La Romana ice-cream shop (350 metres)

Star Rating: 4*
Price: USD 116 – USD 266
Guest Rating: 9
Address: Via Muzio Clementi, 81, Prati, Rome, Italy

Hotel Location

Why You Should Stay in Trastevere

Piazza Trilussa, Ponte Sisto and Painters

Photo| Painting marketplace for artists in Piazza Trilussa, Trastevere| GETTYIMAGES – ALBERTO GUGLIELMI

Located on the eastern side of the River Tiber, Trastevere feels like a small Italian village within Rome. This slice of simple and peaceful provincial life features a variety of welcoming restaurants, small public squares and historic Renaissance buildings. Stroll through the narrow streets to discover hidden bars, talented street performers and unique shops.

Must-Do Trastevere Experiences

  • Marvel at the Roman columns and intricate 12th-century frescoes within the Basilica of Our Lady in Trastevere.
  • Watch street musicians and chill out with locals at Piazza Mastai, Piazza di San Cosimato or Piazza del Ponziani.
  • Tuck into delicious Italian fare at Grazia & Graziella, Ristorante La Piazzetta or Ai Bozzi.

Top Hotels in Trastevere

VOI Donna Camilla Savelli Hotel

VOI Donna Camilla Savelli Hotel

Photo| VOI Donna Camilla Savelli Hotel| Provided by BOOKING.COM

The award-winning VOI Donna Camilla Savelli Hotels captures the small-town charms and hidden luxuries of Trastevere with its intimate gardened courtyard, antique in-room furnishings and welcoming staff. The new Classic Room has a private entry through the Renaissance-style garden and direct access to the Lifestyle Lounge. You can also stay in the Premier Suite for garden views, a separate sitting area and private terrace.

Don’t miss dining at the on-site Bar Bistrot, known for its vegan-friendly breakfast and romantic courtyard seating. You can also relax in a dedicated reading space overlooking the roofs of Trastevere and treat your taste buds to “The Box” Aperitif sensory experience. 

Nearby Attractions

  • Orto Botanico di Roma (450 metres)
  • Museo di Roma in Trastevere (300 metres)
  • Basilica of Our Lady in Trastevere (400 metres) 

Star Rating: 4*
Price: USD 107 – USD 287
Guest Rating: 9.1
Address: Via Garibaldi 27, Trastevere, Lazio, Rome, Italy

Villa Agrippina Gran Melia

Villa Agrippina Gran Meliá, hotel to stay in Rome

Photo| Villa Agrippina Gran Melia| Provided by BOOKING.COM

Want to stay close to the sights of Trastevere and the Vatican City? The 5-star Villa Agrippina Gran Melia offers a close proximity to both these incredible sightseeing neighbourhoods. It also features the opulence and tranquillity of the exclusive Villa Agrippina with its sun-drenched pool surrounded by plush loungers and private cabanas. International, Mediterranean and Italian cuisines are served at the on-site Ossimoro restaurant.

The rooms and suites at this award-winning hotel boast a Spanish-Italian style, including the spacious Deluxe Room with its king-size bed and flat-screen TV. You can upgrade to the Supreme Room with Private Garden or the Junior Suite with a deep-soaking bath. If you really want to splurge, opt for the Grand Suite to enjoy a private terrace, outdoor bath and 360-degree Rome vistas. 

Nearby Attractions

  • Peter’s Square (900 metres)
  • Orto Botanico di Roma (1.2 kilometres)
  • Freni e Frizioni cocktail bar (1.5 kilometres)

Star Rating: 5*
Price: USD 245 – USD 821
Guest Rating: 9
Address: Via Del Gianicolo 3, Trastevere, Lazio, Rome, Italy

Hotel Location

Why You Should Stay in Esquilino

The Baths of Trajan on the Esquiline Hill

Photo| The Baths of Trajan on the Esquiline Hill| GETTYIMAGES – VANNI ARCHIVE

Centred around the bustling Roma Termini train station, Esquilino is a contemporary neighbourhood that retains some of Rome’s best historical attractions while celebrating a multicultural ambience. Along with enthralling museums and prominent landmarks, Esquilino features side-street boutiques and eateries and a range of international restaurants.

Must-Do Esquilino Experiences

  • Stroll up Esquiline Hill, one of the famed Seven Hills of Rome, to admire ancient architecture and wide city vistas.
  • Browse art and artefacts from the Middle and Far East at the National Museum of Oriental Art.
  • Pass under the Arch of Gallienus before ducking into The Druid’s Den for a drink.

Top Hotels in Esquilino

Radisson Blu Es Hotel Roma

Radisson Blu Es Hotel Roma, hotel to stay

Photo| Radisson Blu Es hotel Roma| Provided by ICE PORTAL

Positioned next to the Roma Termini station, Radisson Blu Es Hotel Roma offers easy access to the best sights, restaurants and entertainment in Esquilino. This upscale hotel also boasts more than 230 contemporary rooms and suites, including the affordable Standard Room, executive-style Business Class Room and spacious Junior Suite with a deep-soaking bath Upgrade to the Presidential Suite for a whirlpool bath, private terrace and cosy cocoon sofa.

On-site dining includes a buffet breakfast and spectacular views of Rome at Zest Bar & Restaurant and a refined Mediterranean menu at Restaurant Sette. Don’t forget to indulge in a massage or treatment at Es.sere Spa by Cipriani, which also has a fitness centre, sauna and Jacuzzi. Finish your day with a swim in the rooftop pool overlooking the Eternal City.

Nearby Attractions 

  • National Museum of Oriental Art (750 metres)
  • Esquiline Hill (1.2 kilometres)
  • National Roman Museum (1.1 kilometres) 

Star Rating: 5*
Price: USD 87 – USD 316
Guest Rating: 7.1
Address: Via Filippo Turati, 171, Esquilino, Rome, Italy

NH Collection Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento, hotel to stay in Rome

Photo| NH Collection Roma Palazzo Cinquecento| Provided by ICE PORTAL

NH Collection Palazzo Cinquecento showcases executive Italian luxury and style within the bustling Piazza dei Cinquecento. This unique hotel houses ancient Roman ruins within its tranquil garden and features a sunny rooftop terrace with lounge chairs overlooking the city. You can work out in the on-site gym or dine on Italian and international fare at the Grand Tour restaurant.

Check into the Superior Room for garden or city vistas or upgrade to the Premium Room with Terrace for your own private terrace. There are two room options for families, with a maximum occupancy of six guests in the Family Room XL. Looking for extra luxury? Book the Suite Cinquecento or Junior Suite with View.

Nearby Attractions

  • National Roman Museum (220 metres)
  • Indipendenza Art Gallery (400 metres)
  • Palazzo Massimo alle Terme (550 metres)

Star Rating: 5*
Price: USD 180 – USD 477
Guest Rating: 9.1
Address: Piazza Dei Cinquecenti 90, Esquilino, Rome, Italy

Hotel Location

Why You Should Stay in Campo Marzio

Fontana della Barcaccia in Piazza di Spagna with Spanish Steps

Photo| Fontana della Barcaccia in Piazza di Spagna with Spanish Steps| GETTYIMAGES – MINEMERO

Campo Marzio is one of the best neighbourhoods in Rome to explore during the day when its historic piazzas reveal stunning Renaissance and Baroque architecture. This affluent neighbourhood is frequented by fashionistas and wealthy locals who shop at its luxe boutiques and frequent the fine-dining Italian restaurants.

Must-Do Campo Marzio Experiences

  • Sit on the historic Spanish Steps while watching the street performers in the piazza below.
  • Browse the designer boutiques along Via del Corso or within the popular Galleria Alberto Sordi shopping mall.
  • Discover fascinating history about Napoleon Bonaparte and his family at the Napoleonic Museum.

Top Hotels in Marzio

J K Place Roma

J K Place Roma, hotel to stay in rome

Photo| JK Place Roma| Provided by BOOKING.COM

The luxurious J K Place Roma is filled with eye-catching paintings and sculptures, which complement its stylish furnishings and dedicated service. The rooms and suites are also furnished with a contemporary and artistic focus, featuring plush furniture and unique in-room artwork. Certain rooms, such as the JKClassic Balcony and Superior Balcony Double, also have private balconies.

Want the epitome of J K Place Roma’s opulence? Stay in the JKMaster Balcony Room, which has a large, furnished balcony, along with an Italian marble bathroom and rosewood canopy bed. Don’t forget to indulge in the sumptuous Sunday Brunch or Italian-inspired Chef’s Menu at the on-site JKCafe, which also serves signature cocktails. 

Nearby Attractions

  • Spanish Steps (550 metres)
  • Mausoleum of Augustus (290 metres)
  • Galleria Alberto Sordi (600 metres) 

Star Rating: 5*
Price: USD 439 – USD 1,244
Guest Rating: 10
Address: Via di Monte d’Oro 30, Campo Marzio, Rome, Italy

Margutta 19 – Small Luxury Hotels of the World

Margutta 19 – Small Luxury Hotels of the World

Photo| Margutta 19, Small Luxury Hotels of the World| Provided by BOOKING.COM

Part of the Small Luxury Hotels of the World, Margutta 19 offers intimate accommodation on the art-infused Via Margutta. This former palace has been turned into a first-class hotel, where you can watch films in the on-site theatre and sip cocktails in the serene Borghese garden. Don’t miss having a meal at the Assaggia restaurant, which serves traditional dishes made with centuries-old family recipes.

The Deluxe Room is the most affordable option and features a king-size bed and a travertine marble bathroom. Upgrade to the Deluxe Suite for a freestanding tub and walk-in shower or opt for the Garden Suite to enjoy a private gardened terrace. 

Nearby Attractions

  • Spanish Steps (550 metres)
  • Pincio Promenade (750 metres)
  • Goethe House (200 metres) 

Star Rating: 5*
Price: USD 367 – USD 699
Guest Rating: 9.4
Address: Via Margutta 19, Campo Marzio, Rome, Italy

Hotel Location

The Best of Rome at Your Doorstep

Rome is undoubtedly one of the world’s top bucket-list destinations, providing you with an array of world-class attractions, restaurants and shops. The six neighbourhoods featured above each provide their own unique environments while keeping you close to some of the city’s best sights. The most popular hotels in each neighbourhood offer incredible luxury with their on-site facilities and enough room options to suit all types of travellers.

Where do you prefer to stay in Rome? Let us know in the comments.

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