Vacation rentals in Panama City

Search and compare Panama City, Panama vacation rentals from hundreds of travel sites on HotelsCombined and save.

...and more

Learn why travelers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customize your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Travel insights for vacation rentals in Panama City

Use our HotelsCombined data-powered tips to help you find your next vacation rental in Panama City.

What is the cheapest month to book a vacation rental in Panama City?

The cheapest month to book a vacation rental in Panama City is May ($65). Conversely, the most expensive month to stay in Panama City is April ($976).

What is the cheapest day to stay in a vacation rental in Panama City?

The cheapest day to stay in Panama City is Wednesday ($88). On the other hand, travelers can expect to pay the most on Thursday, when the average nightly price is $141.

How far ahead should you book a vacation rental in Panama City?

Save money by booking a vacation rental at least 31 days before your trip to Panama City. The lowest price found when booking 31 days ahead was $46 per night.

Cheapest vacation rentals in Panama City, Panama

Discover affordable stays in Panama City that provide a quality experience without breaking the bank. Hotels in Panama City can be found for as low as $120 per night. There is currently one property in Panama City that can be booked for this price. Marriott Executive Apartments Panama City, Finisterre is one of the hotels that can be booked for the lowest price in Panama City. Price data was last updated on July 27, 2026
Out of the vacation rentals in Panama City we've come across, these properties are priced the lowest. Consider alternative dates if you're able to compare prices.
Panama City, Panama
2.3 mi from city centre
Air Conditioning
$162
Avg. per night

Other accommodations in Panama City

Find the perfect vacation rental for your stay in Panama City. There are 1,443 hotels in Panama City and price data was last updated on July 27, 2026. The average price for a hotel in Panama City is $205/night.
Esquina de Ave B y Calle 12, Panama City, Panama
2.2 mi from city centre
Free Wi-Fi
$37
Avg. per night
Bella Vista,Campo Alegre 10600 N 5A Consul Finl Poste 5B 05 22 51 Distr. En Mano IT. 645 Med 99678688, Panama City, Panama
0.5 mi from city centre
Free Wi-Fi
Parking
$16
Avg. per night
21 C. Alberto Navarro, Panama City, Panama
0.3 mi from city centre
Free Wi-Fi
Airport shuttle
$60
Avg. per night
Calle Ramon H Jurado Edifico P, Panama City, Panama
1.0 mi from city centre
Free Wi-Fi
Parking
$162
Avg. per night
Calle Eusebio A. Morales y Calle 55, Panama City, Panama
0.2 mi from city centre
Free Wi-Fi
Parking
$86
Avg. per night
El Cangrejo Calle Eusebio A. Morales 31,Calle Eusebio A. Morales, Panama, Panama City, Panama
0.2 mi from city centre
Free Wi-Fi
Parking
$44
Avg. per night
Panama City, Panama
2.3 mi from city centre
Air Conditioning
$162
Avg. per night

Where to stay in Panama City

Explore different neighborhoods and areas within Panama City to find the perfect location for your stay. Map data was last updated on July 27, 2026.
Navigate to the areas in Panama City you plan to visit to find vacation rentals that are close by. Users can click on a vacation rental's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Panama City

Find useful tips and insights about staying in Panama City to help you make the most of your experience. FAQs were last updated on July 27, 2026.

  • How much does a vacation rental in Panama City cost?

    $174 per night is how much a vacation rental in Panama City costs, on average. $9 per night was the cheapest price recently found by our users, though anything for $134 per night or less is a good deal. Keep in mind that Panama City vacation rental prices fluctuate throughout the year: the most expensive month to book is September, and the cheapest time to book is July.

  • What is the best Panama City vacation rental?

    La Isabela Suites has a 9.5 rating from 234 users, making it the best Panama City vacation rental based on our data.

  • What’s the closest vacation rental to Panama City Tocumen Intl Airport?

    It’s only 13.2 mi from Panama City Tocumen Intl Airport to La Isabela Suites (the nearest Panama City vacation rental to the airport).

  • What part of Panama City is best to stay in?

    The best neighborhood to stay in Panama City is Bella Vista, according to our user data. 9% of our users who looked for vacation rentals in Panama City searched for properties in the Bella Vista area. If you’re also interested in booking a vacation rental in Bella Vista, consider the Marriott Executive Apartments Panama City, Finisterre - the neighborhood’s most popular rental property.

  • What’s the most popular vacation rental in Panama City near Los Pueblos Commercial Center?

    If you’re looking for a vacation rental close to Los Pueblos Commercial Center while in Panama City, then the most popular is La Isabela Suites with a 9.5/10 review score from 234 users. The distance from Los Pueblos Commercial Center to La Isabela Suites is 8.7 mi.

See more FAQs

Find better results for your stay in Panama City

Explore these cities in Panama

Looking to explore Panama during your trip? These are other popular cities nearby that HotelsCombined users visit