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Muscatine 4-star Hotels

Compare rates for 4-star hotels in Muscatine, IA from hundreds of popular travel sites on HotelsCombined.

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Travel insights for hotels in Muscatine

Use our HotelsCombined data-powered tips to help you find your next hotel in Muscatine.

What is the cheapest month to book a hotel in Muscatine?

The cheapest month to book a hotel in Muscatine is January ($101). Conversely, the most expensive month to stay in Muscatine is October ($132).

What is the cheapest day to stay in a hotel in Muscatine?

The cheapest day to stay in Muscatine is Saturday ($91). On the other hand, travelers can expect to pay the most on Tuesday, when the average nightly price is $186.

How much is a hotel in Muscatine tonight?

Users have found prices for hotels in Muscatine tonight starting as low as $101, rising to an average cost of $182, based on searches in the last 72 hours. Prices start from $200 for a 4-star hotel in Muscatine for tonight.
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Cheapest 4-star hotels in Muscatine

Discover affordable 4-star hotels in Muscatine that provide a quality experience without breaking the bank. 4-star hotels in Muscatine can be found for as low as $189 per night. Price data was last updated on August 7, 2025
These are the lowest-priced 4-star hotels our users have recently found in Muscatine. Prices may vary based on dates selected and hotel location.
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

119 Mississippi Drive West, Muscatine, IA, United States
0.3 mi from city centre
Pool
Free Wi-Fi
Parking
$189
Avg. per night
View Deal

Other star-rated hotels in Muscatine

Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on August 7, 2025.
Not set on a 4-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Muscatine based on hotel class.
3 stars
Strawberry Farm B and B
Strawberry Farm B and B

Strawberry Farm B and B

3402 Tipton Road, Muscatine, IA, United States
$169
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Hampton Inn Muscatine
Hampton Inn Muscatine

Hampton Inn Muscatine

3303 North Port Drive, Muscatine, IA, United States
$132
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2 stars and under
Comfort Inn Muscatine near Hwy 61
Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61

115 Cleveland Street, Muscatine, IA, United States
$85
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Best Western Pearl City Inn
Best Western Pearl City Inn

Best Western Pearl City Inn

305 Cleveland Street, Muscatine, IA, United States
$93
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AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

3115 Highway 61 North, Muscatine, IA, United States
$74
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Other accommodations in Muscatine

Find deals on places to stay in Muscatine that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on August 7, 2025.
Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Muscatine.
Strawberry Farm B and B
Strawberry Farm B and B

Strawberry Farm B and B

3402 Tipton Road, Muscatine, IA, United States
2.2 mi from city centre
Free Wi-Fi
Air Conditioning
$169
Avg. per night
View Deal
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

119 Mississippi Drive West, Muscatine, IA, United States
0.3 mi from city centre
Pool
Free Wi-Fi
Parking
$189
Avg. per night
View Deal

Where to stay in Muscatine

Explore different areas within Muscatine to find the perfect location for your stay. Map data was last updated on August 7, 2025.
The map below shows all 4-star hotels in Muscatine. Zoom in to find popular attractions and click on a nearby hotel for more information about the property.

Facts about 4-star hotels in Muscatine

Find useful tips and insights about 4-star hotels in Muscatine to help you make the most of your experience. FAQs were last updated on August 7, 2025.

  • What is the cheapest 4-star hotel in Muscatine?

    In Muscatine, you can stay at The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel, the most affordable 4-star hotel, priced from $189 per night.

  • What is the best 4-star hotel in Muscatine?

    For travelers seeking the top 4-star experience in Muscatine, The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel stands out with its 8.8 user rating and an average nightly rate of $276.

Stay elsewhere in Muscatine

Consider these popular 3-star hotels in Muscatine

Stay at one of these Muscatine 3-star hotels that users have found on HotelsCombined.
Hampton Inn Muscatine
Strawberry Farm B and B

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